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Repercussões dos microplásticos e nanoplásticos nos sistemas gastrointestinal, circulatório e respiratório: Um novo potencial de exposição

Research Society and Development 2024 Score: 45 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
RAFAEL VITOR CRISTINO DA SILVA, Carla Manuella Campelo Guerra Queiroz Campos, Arthur Barbosa Mota, Caio Pinheiro Ferreira Tenório, Daniele Schiavi, Gabriela Menezes, Helena Pôrto de Assis, Pedro R Salerno, S. Rodrigues, Yasmin Duarte Costa

Summary

This integrative review examined the effects of microplastics and nanoplastics on the gastrointestinal, circulatory, and respiratory systems, drawing on studies indexed in PubMed, SciELO, LILACS, and Cochrane databases. The review summarized the routes of contamination and health consequences of plastic particle exposure for these major organ systems.

Objetivo: Compreender as formas de contaminação e as consequências dos microplásticos (MPs) e nanoplásticos (NPs) para os sistemas gastrointestinal, respiratório e cardiovascular. Métodos: Revisão integrativa através das plataformas de base de dados Pubmed, SciELO, LILACS e Cochrane. A pesquisa foi feita através da estratégia de pesquisa: (“human health”) AND (“cell interaction”) OR (“microplastics”). Foram encontrados um total de 489 artigos. Após a aplicação dos critérios de inclusão e exclusão, foram selecionados 25 artigos, sendo removidos 20 artigos após a análise inicial. Isso totalizou 5 artigos para análise completa. Resultados: Evidencia-se extensos danos das partículas plásticas na saúde humana. No sistema gastrointestinal, o aumento da inflamação local causa disfunção da barreira e redução da digestão de determinadas macromoléculas. No sistema respiratório, a redução da depuração mucociliar corrobora para um acréscimo de patógenos e uma permanência de detritos, provenientes do ar externo, no pulmão. No sistema cardiovascular, alterações da frequência cardíaca, bem como o aumento do risco de trombose são achados da presença dos MPs e NPs. Considerações finais: Conclui-se uma visão integrada dos danos promovidos pelos MPs e NPs e suas interações com as células humanas, porém ainda não existem grandes evidências que permitam avaliar a extensão total dos danos.

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