0
Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Policy & Risk Reproductive & Development Sign in to save

Exploring the impact of polystyrene microplastics on human health: unravelling the health implications of polystyrene microplastics (PS-MPs): a comprehensive study on cytotoxicity, reproductive health, human exposure, and exposure assessment

Toxicology Research 2024 6 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Saurabh Dilip Bhandare

Summary

This study explores the various ways polystyrene microplastics can affect human health, including through impacts on cells, reproductive tissues, and cumulative exposure from food and consumer products. Researchers found evidence that toxic chemicals leaching from polystyrene can enter the body through multiple routes and accumulate over time. The findings emphasize the importance of standardized methods for monitoring human microplastic exposure.

Polymers
Body Systems
Models

This investigation explores the various impacts that polystyrene microplastics (PS-MPs) have on human health. As most of the plastic materials affect human health when they release leachable toxic substances that affect human health, this causes a negative effect that determines poor health conditions and leads to health hazards associated with plastic toxins routed in the human body, such as: Polychlorinated Biphenyls, Polybrominated Biphenyls etc. The study includes micro-plastic exposure assessment on testicular structure analysis, and cytotoxicity evaluations of different human cell types. The findings clarified the possible dangers of PS-MPs exposure from food, medications, and common products, emphasising the necessity of standard specimen handling procedures for precise biomonitoring.

Sign in to start a discussion.

More Papers Like This

Article Tier 2

Exposure of microplastic at levels relevant for human health : cytotoxicity and cellular localization of polystyrene microparticles in four human cell lines

Researchers tested the cytotoxicity of polystyrene microplastics on four human cell lines at concentrations relevant to real-world human exposure from food, water, and packaging. At environmentally realistic doses, microplastics were taken up by cells but did not cause significant toxicity, though higher concentrations did produce cell damage, suggesting that current exposure levels may be near a threshold of concern.

Systematic Review Tier 1

A review of potential human health impacts of micro- and nanoplastics exposure

This systematic review summarized 133 studies on how micro- and nanoplastics affect human health based on mammalian research. The evidence points to cell damage, inflammation, gut disruption, and reproductive harm, though most studies focused on polystyrene particles and more research is needed on other common plastic types.

Article Tier 2

Review of the toxic effects and mechanisms of polystyrene micro/nanoplastics across multiple animal species

This review comprehensively examines the toxic effects of polystyrene micro- and nanoplastics across marine animals, freshwater species, soil organisms, and mammals. Researchers found that these particles can cause damage at multiple biological levels, affecting the digestive, respiratory, nervous, reproductive, and circulatory systems. The study highlights the widespread environmental presence of polystyrene plastics and the need to better understand how they harm living organisms.

Article Tier 2

The effects of polystyrene microplastics on human intestinal cells health and function

This study examined how polystyrene microplastics affect normal and cancer intestinal cells, addressing a gap left by previous research that used only cancer cell lines and pristine plastics. The work evaluated microplastic toxicity under more realistic conditions including digestive system biotransformation, assessing effects on nutrient uptake and cellular function.

Systematic Review Tier 1

Can Mammalian Reproductive Health Withstand Massive Exposure to Polystyrene Micro- and Nanoplastic Derivatives? A Systematic Review

This systematic review examined how polystyrene micro- and nanoplastics affect reproductive health in mammals. The evidence from animal studies shows these particles can cause oxidative stress, inflammation, and hormonal imbalances in reproductive organs, raising concerns about potential effects on human fertility.

Share this paper