Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Detection Methods Human Health Effects Marine & Wildlife Nanoplastics Remediation Reproductive & Development Sign in to save

The Effect of Exposure to Polystyrene Nanoplastics on Cytokine Levels and Reproductive System of Male Tilapia

Tropical Journal of Natural Product Research 2024 5 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Raden Joko Kuncoroningrat Susilo, Alfiah Hayati, Alfiah Hayati, Alfiah Hayati, Alfiah Hayati, Manikya Pramudya, Manikya Pramudya, Alfiah Hayati, Alfiah Hayati, Alfiah Hayati, Manikya Pramudya, Raden Joko Kuncoroningrat Susilo, Manikya Pramudya, Widi Pangestu Wilujeng, Manikya Pramudya, Manikya Pramudya, Manikya Pramudya, Alfiah Hayati, Sugiharto Sugiharto, Widi Pangestu Wilujeng, Firli Rahmah Primula Dewi, Manikya Pramudya, Manikya Pramudya, Firli Rahmah Primula Dewi Firli Rahmah Primula Dewi Firli Rahmah Primula Dewi, Firli Rahmah Primula Dewi Firli Rahmah Primula Dewi Firli Rahmah Primula Dewi, Manikya Pramudya, Sugiharto Sugiharto, Firli Rahmah Primula Dewi, Raden Joko Kuncoroningrat Susilo, Firli Rahmah Primula Dewi, Manikya Pramudya, Firli Rahmah Primula Dewi Sugiharto Sugiharto, Firli Rahmah Primula Dewi, Widi Pangestu Wilujeng, Widi Pangestu Wilujeng, Alfiah Hayati, Firli Rahmah Primula Dewi Alfiah Hayati, Bayyinatul Muchtaromah, Bayyinatul Muchtaromah, Manikya Pramudya, Bayyinatul Muchtaromah, Raden Joko Kuncoroningrat Susilo, Alfiah Hayati, Alfiah Hayati, Firli Rahmah Primula Dewi, Raden Joko Kuncoroningrat Susilo, Firli Rahmah Primula Dewi Firli Rahmah Primula Dewi, Firli Rahmah Primula Dewi Firli Rahmah Primula Dewi, Manikya Pramudya, Bayyinatul Muchtaromah, Firli Rahmah Primula Dewi Bayyinatul Muchtaromah, Bayyinatul Muchtaromah, Alfiah Hayati, Manikya Pramudya, Alfiah Hayati, Alfiah Hayati, Alfiah Hayati, Alfiah Hayati, Alfiah Hayati, Alfiah Hayati, Bayyinatul Muchtaromah, Manikya Pramudya, Alfiah Hayati, Sugiharto Sugiharto, Firli Rahmah Primula Dewi, Firli Rahmah Primula Dewi Sugiharto Sugiharto, Manikya Pramudya, Firli Rahmah Primula Dewi, Firli Rahmah Primula Dewi

Summary

Researchers fed male tilapia fish different doses of polystyrene nanoplastics for 25 days and examined the effects on their reproductive systems. While inflammatory markers in the blood were not significantly affected, the nanoplastics caused a notable reduction in the number of sperm-producing cells in testicular tissue. The study suggests that nanoplastic exposure may pose risks to reproductive health in fish even without triggering obvious immune responses.

Polymers

Body Systems

Immune Reproductive

Models

Fish other

Several studies demonstrated adverse effects associated with exposure to polystyrene nanoplastics (NPs), such as toxicity, inflammation, or other health-related concerns. This study aims to analyse the impact of NPs exposure on pro-inflammatory cytokine levels and testicular histology in tilapia gonads. Twenty-four male tilapias were used in this study and divided into four groups, including a control (commercial pellets only) and three treatment groups (commercial feed mixed 0.5, 1.0 and 2.0 µL/kg of NPs, respectively) for 25 days. Blood sample was used to tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-ɣ) levels analysis. Histology of testicular tissue was prepared with hematoxylin and eosin (HE) staining. The results showed that NPs exposure has no significant influence of TNF-α and IFN-ɣ levels. The levels of TNF-α on the control (1.6 ± 0.3 ng/mL) and the treatment groups from low to high concentration (1.7± 0.4; 1.7 ± 0.4; and 1.6 ± 0.3 ng/mL) and the levels of IFN-γ control (16.7 ± 2.8 ng/mL) and the treatment groups (19.1 ± 5.3; 18.7 ± 4.2; and 19.8 ± 3.5 ng/mL). Polystyrene nanoplastics exposure can reduce the number of spermatogenic cells. Spermatogonia cells was decreased from 27.5 ± 0.9 to 13.1 ± 1.1 cells/cyst. Spermatocyte cell was decreased from 57.6 ± 0.6 to 18.5 ± 0.3 cells/cyst. Spermatid cells was decreased from 86.8 ± 2.7 to 38.5 ± 2.7. In conclusion, exposure to multiple doses of NPs for 25 days did not increase pro-inflammatory cytokines levels in the blood serum of tilapia, but it caused histological changes in the gonads of fish.

Read via DOI Download PDF

Share this paper

Post Share Share Pin Email