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Intravenous hypertonic fluids as a source of human microplastic exposure
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Researchers tested 13 brands of intravenous hypertonic fluid solutions and found microplastics in every single sample, with an average of about 63 particles per liter. The particles were mostly fragments of various plastics ranging from 0.04 to 2.37 millimeters in size. This is especially concerning because IV fluids bypass the body's natural barriers like the gut and lungs, delivering microplastics directly into the bloodstream of hospital patients.
This study investigates the presence of microplastics (MPs) in hypertonic fluid solutions, a widely used medical treatment packaged predominantly in plastic. For this purpose, in this study, 13 hypertonic fluid samples from different brands and two different types of packaging (polypropylene and polyvinyl chloride) were analyzed using visual particle counting, µ-Raman microscopy and ATR-FTIR. The results reveal the pervasive presence of MPs in all samples, with an estimated average concentration of 62.82 ± 72.38 MPs/1000 mL. There was no statistically significant difference in MP concentration between PP and PVC packaging. The particles predominantly consisted of fragments (74.1%) and fibers (25.9%), ranging in size from 0.04 to 2.37 mm. µ-Raman analysis identified 12 synthetic polymers as well as cellulose, with polyethylene and cellulose being the most prevalent. In conclusion, this study underscores the alarming presence of MPs in hypertonic fluid solutions, raising concerns about potential health risks.
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