Microplastic residues in clinical samples: A retrospection on sources, entry routes, detection methods and human toxicity

Microplastics in human body: a narrative on routes of exposure to contamination and potential health effects

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Tiny plastic particles from our environment and food are getting into our bodies through eating, drinking, and breathing, and this review of existing research shows they've been found in organs like the liver, heart, and lungs. Scientists are concerned that as these particles build up over time, they may cause cell damage, inflammation, and stress on the body, though more research is still needed to fully understand the long-term health risks. The takeaway: microplastic exposure is nearly impossible to avoid completely, but reducing contact with plastic packaging and products may help limit how much ends up in your body.

Microplastic Pollution: Human Exposure, Uptake, Accumulation Pathways, and Potential Health Consequences

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Researchers reviewed the exposure routes, uptake mechanisms, and accumulation pathways of microplastics in the human body, concluding that the ubiquitous presence of these particles warrants urgent investigation into their long-term ecological and health consequences.

Microplastics and Human Health: A Comprehensive Review of Exposure Pathways, Biological Mechanisms, and Clinical Implications

Biochemical Effects of Microplastics on Human Health: A Comprehensive Review

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A comprehensive review documents how microplastics enter the human body through ingestion, inhalation, and skin contact, then reach the lungs, liver, kidneys, brain, and reproductive organs, triggering oxidative stress, inflammation, endocrine disruption, and genotoxicity. These biochemical pathways link microplastic exposure to serious chronic conditions including metabolic syndrome, neurodegenerative disease, reproductive dysfunction, and cancer.

Detection and characterization of microplastics and nanoplastics in biological samples

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Researchers reviewed current methods for detecting and characterizing microplastics and nanoplastics in biological samples, finding that most techniques are optimized for environmental media like water and perform poorly in complex biological matrices, and recommending improved workflows for digestion, separation, enrichment, and analysis of particles in organisms and human tissues.