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Development of a polystyrene-based microplastic model for bioaccumulation and biodistribution study using radiotracing and nuclear analysis method
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Researchers developed a radiolabeled polystyrene microplastic model to track how microplastics move through and accumulate in living organisms. The study suggests that using radioactive tracers like iodine-131 allows for real-time, sensitive monitoring of microplastic behavior in biological systems, offering a more efficient alternative to conventional tracking methods.
The investigation of micro or nano plastics behavior in the environment is essential to minimize the hazards of such pollutants on humans. While the conventional method requires sophisticated procedures and a lot of animal subjects, the nuclear technique confers a sensitive, accurate, and real-time method using radiolabeled micro or nano plastics as a tracer. In this study, polystyrene sulfonate-based microplastic (PSM) was developed with a size of around 3.6 μm, followed by radiolabeling with iodine-131 (I) or zinc-65 (Zn) for microplastic radiotracer model. After a stability study in seawater, phosphate buffer saline (PBS), and human serum albumin (HSA) for fifteen days, PSM-I remained stable (>90 %), except in HSA (50-60 % after day-9), while PSM-Zn was unstable (<50 %).
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