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Farming Activities and Risk of Inflammatory Bowel Disease: A French Nationwide Population-based Cohort Study
Summary
Researchers conducted a large population study in France examining whether farming activities are associated with increased risk of inflammatory bowel disease. While the study identified farming as a potential risk factor, the specific exposures driving this link remain unclear. The authors highlight that further research into agricultural exposures, including pesticides, pathogens, and micro- and nanoplastics, could help identify occupational risk factors for gut health conditions.
Further research regarding specific farming activities and exposures likely to modify the microbiota [eg, pesticides, pathogens] is required to identify potential occupational risk factors [agricultural exposome] for IBD. Exposure to Mycobacterium avium subspecies paratuberculosis, Cryptosporidium, environmental toxins, micro/nanoplastics, and pesticides represents promising research avenues.