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Natural and Synthetic Polymers for Biomedical and Environmental Applications

Polymers 2024 366 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 75 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Galina Satchanska, Slavena Davidova, Petar Petrov

Summary

This review covers both natural and synthetic polymers used in biomedical and environmental applications, from drug delivery systems to food packaging. It discusses how biodegradable plastics like polylactic acid are being developed for medical uses, while also noting environmental concerns. Understanding how these polymers behave in the body and environment is relevant to the broader question of how plastic materials interact with human health.

Polymers

Natural and synthetic polymers are a versatile platform for developing biomaterials in the biomedical and environmental fields. Natural polymers are organic compounds that are found in nature. The most common natural polymers include polysaccharides, such as alginate, hyaluronic acid, and starch, proteins, e.g., collagen, silk, and fibrin, and bacterial polyesters. Natural polymers have already been applied in numerous sectors, such as carriers for drug delivery, tissue engineering, stem cell morphogenesis, wound healing, regenerative medicine, food packaging, etc. Various synthetic polymers, including poly(lactic acid), poly(acrylic acid), poly(vinyl alcohol), polyethylene glycol, etc., are biocompatible and biodegradable; therefore, they are studied and applied in controlled drug release systems, nano-carriers, tissue engineering, dispersion of bacterial biofilms, gene delivery systems, bio-ink in 3D-printing, textiles in medicine, agriculture, heavy metals removal, and food packaging. In the following review, recent advancements in polymer chemistry, which enable the imparting of specific biomedical functions of polymers, will be discussed in detail, including antiviral, anticancer, and antimicrobial activities. This work contains the authors' experimental contributions to biomedical and environmental polymer applications. This review is a vast overview of natural and synthetic polymers used in biomedical and environmental fields, polymer synthesis, and isolation methods, critically assessessing their advantages, limitations, and prospects.

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