Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Gut & Microbiome Policy & Risk Sign in to save

mTOR signaling pathway regulation HIF-1 α effects on LPS induced intestinal mucosal epithelial model damage

BMC Molecular and Cell Biology 2024 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 40 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Zeyong Huang, Zeyong Huang, Rui He, Wenbin Teng, Wenbin Teng, Kai Xie, Liuxu Yao, Liuxu Yao, Kai Xie, Kai Xie, Suqin Hang, Rui He, Yuhong Li

Summary

This paper is not about microplastics; it investigates how the HIF-1α protein modulates intestinal cell damage caused by bacterial lipopolysaccharide (LPS) through the mTOR/P70S6K signaling pathway — a molecular biology study of gut inflammation.

This study once again confirmed that HIF-1α alleviates LPS-induced mucosal epithelial model damage through P70S6K signalling pathway. It is of great value to explore whether HIF-2α plays crucial roles in the regulation of mucosal epithelial model functions in the future.

Read via DOI Download PDF

Share this paper

Post Share Share Pin Email