Enterohepatic circulation of nanoplastics induced hyperplasia, epithelial-mesenchymal transition, and neutrophil extracellular traps in gallbladder

Impact of Microplastics on the Severity of Intestinal Inflammation in Mice

Impact of Micro-nanoplastics on Gut and Immune Function

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This review examined how micro- and nanoplastics disrupt gut microbiota and immune function across aquatic and terrestrial vertebrates, with implications for human health. Because the gut microbiome governs immune regulation and metabolic health, microplastic-induced dysbiosis represents a plausible mechanism by which plastic ingestion could drive systemic inflammation and disease beyond the GI tract.

Environmental Nanoplastics Induce Microglia Activation and Inflammatory Responses

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Tiny plastic particles from pollution (called nanoplastics) can travel all the way into the brain, where new research shows they trigger the brain's immune cells to become overactive and cause inflammation. This matters because chronic brain inflammation has been linked to conditions like memory problems and neurodegenerative disease, raising concerns about the long-term effects of the plastic pollution we're increasingly exposed to in daily life.

Nanoplastics target lung monocytes, disrupting immune dynamics

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This research analyzed how business model innovation could transform the plastics industry toward greater circularity and reduced environmental impact. The study identified game-changing business strategies that could decouple economic growth from plastic waste generation, with examples from industry leaders adopting circular approaches.

Micro- and Nanoplastics as Disruptors of Digestive and Hepatopancreatic Homeostasis: Insights into the Plastic-Gut-Liver Axis

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Researchers reviewed how micro- and nanoplastics disrupt the gut-liver axis by compromising intestinal barrier integrity, promoting microbiota dysbiosis, and enabling microbial translocation via portal circulation that triggers hepatic inflammation, metabolic reprogramming, and potential carcinogenic processes, while also noting emerging evidence of pancreatic and multi-organ involvement.