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The Potential Presence of Microplastics in Daily Food and Beverage Consumption May Lead to Alzheimer's disease in The Thai Population
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This review examines the potential presence of microplastics in everyday food and beverages including seafood, tap water, bottled water, and packaged foods, summarizing current contamination data and dietary exposure estimates. The authors highlight the need for standardized methods to improve comparability across studies.
Environmental issues have become a global crisis. The amount of plastic used has relentlessly increased due to its advantages such as low cost production, lightweight, strength and durability. However, high usage of plastic contributes to microplastics, which are small particles that are difficult to detect and may be found in daily food and beverage consumption. Consequently, it is prone to accumulate in our body and affect our organs, including the brain. From recent studies, there are some possibilities that microplastics exposure can promote human brain damage, including Alzheimer’s. Due to microplastic concerns, this study aims to find out the relation between microplastics in daily food and beverage consumption and Alzheimer’s disease in the Thai population by collecting the responses (509 participants) through a questionnaire. The questionnaire uses Likert scales to evaluate the quantities of daily microplastics consumption, packaging, and Alzheimer assessment. As a result, the data revealed that microplastics consumption has a link to the risk of developing Alzheimer’s disease. We show that microplastics consumption and plastic containers are positively correlated for the Thai population. Consequently, in the course of time, it can lead to other causes of Alzheimer’s disease diagnosed when microplastics are accumulated in the human body. Moreover, it can raise social awareness through campaigns or policies on plastics used which have to be immediately reduced.
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Researchers examined brain tissue from 16 deceased donors in northeast China and found microplastics, including polyethylene, PVC, polystyrene and polypropylene, in all samples. Higher levels of two plastic types were linked to higher amounts of a protein associated with Alzheimer's disease, though this does not prove the plastics caused the protein changes.
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This review examines how environmental contaminants, including microplastics, may contribute to Alzheimer's disease risk. Along with air pollutants, toxic metals, and pesticides, plastics and microplastics are identified as potential risk factors that may promote brain inflammation and neurodegeneration. The review explores the molecular mechanisms behind these effects and suggests strategies to reduce the brain health impacts of environmental contaminants.
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This review examines emerging evidence that chronic microplastic exposure may be a previously overlooked risk factor for dementia. Microplastics can cross the blood-brain barrier and may promote brain damage through oxidative stress, inflammation, and by accelerating the buildup of amyloid plaques linked to Alzheimer's disease, with studies finding higher microplastic levels in the brains of dementia patients compared to controls.
The Role of Emerging Environmental Contaminants on Alzheimer’s Disease
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This review examined the role of emerging environmental contaminants, including microplastics, in the development and progression of Alzheimer's disease. The authors discussed mechanisms including oxidative stress, neuroinflammation, and blood-brain barrier disruption as potential pathways linking environmental exposures to AD pathogenesis.
Low-Density Polyethylene Microplastics in the Blood Seems not Induce Alzheimer’s Disease in Wistar Rat
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Researchers investigated whether low-density polyethylene microplastics in the blood trigger Alzheimer's disease in Wistar rats, noting that these particles enter the human body through contaminated food sources including table salt, fish, tea bags, and drinking water.
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