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Gastrointestinal problems in a valproic acid-induced rat model of autism: From maternal intestinal health to offspring intestinal function

World Journal of Psychiatry 2024 7 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Sha Li, Nan Zhang, Li Wang, Han-Lai Zhang, Han-Lai Zhang, Xiaoxi Wang

Summary

Researchers studied gastrointestinal problems in a rat model of autism and found connections between maternal gut inflammation, disrupted gut bacteria, and digestive issues in offspring. The study suggests that intestinal health problems seen in autism spectrum conditions may have roots in the maternal environment during development. Further research is needed to better understand how maternal gut health influences digestive function in neurodevelopmental conditions.

Body Systems

Digestive Immune

Models

Rat

GI problems in ASD may be associated with maternal intestinal inflammation and microbiota abnormality. Future research is required to find more evidence on the etiology and treatment of GI problems in ASD.

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