Impact of Nanoplastic Particles on Macrophage Inflammation and Intestinal Health in a Mouse Model of Inflammatory Bowel Disease
Nanomaterials2024
8 citations
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Score: 55
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Marlene Schwarzfischer,
Rälf Kaegi,
Marlene Schwarzfischer,
Marlene Schwarzfischer,
Rälf Kaegi,
Tano S. Ruoss,
Tano S. Ruoss,
Gerhard Rogler,
Anna Niechcial,
Rälf Kaegi,
Anna Niechcial,
Rälf Kaegi,
Rälf Kaegi,
Anna Niechcial,
Rälf Kaegi,
Sung Sik Lee,
Rälf Kaegi,
Anna Niechcial,
Rälf Kaegi,
Rälf Kaegi,
Rälf Kaegi,
Sung Sik Lee,
Marcin Wawrzyniak,
Marcin Wawrzyniak,
Rälf Kaegi,
Rälf Kaegi,
Rälf Kaegi,
Rälf Kaegi,
Andrea Laimbacher,
Rälf Kaegi,
Andrea Laimbacher,
Andrea Laimbacher,
Andrea Laimbacher,
Rälf Kaegi,
Sung Sik Lee,
Rälf Kaegi,
Rälf Kaegi,
Kirstin Atrott,
Kirstin Atrott,
Kirstin Atrott,
Kirstin Atrott,
Roberto Manzini,
Rälf Kaegi,
Roberto Manzini,
Roberto Manzini,
Roberto Manzini,
Marijn Wilmink,
Yasser Morsy,
Luise Linzmeier,
Rälf Kaegi,
Luise Linzmeier,
Rälf Kaegi,
Rälf Kaegi,
Yasser Morsy,
Silvia Lang,
Gerhard Rogler,
Silvia Lang,
Silvia Lang,
Rälf Kaegi,
Gerhard Rogler,
Michael Scharl,
Rälf Kaegi,
Marianne R. Spalinger
Michael Scharl,
Marianne R. Spalinger
Summary
Researchers studied the effects of nanoplastic ingestion in a mouse model of inflammatory bowel disease and found that the particles influenced macrophage inflammation and intestinal health. The findings offer some reassurance that typical levels of nanoplastic exposure may not dramatically worsen bowel disease symptoms. However, the study notes that individuals with higher plastic intake due to lifestyle or dietary habits could face different long-term gastrointestinal risks.
Our findings from animal models offer some reassurance to IBD patients regarding the effects of NP ingestion. However, variations in lifestyle and dietary habits may lead to significantly higher plastic intake in certain individuals, raising concerns about potential long-term gastrointestinal effects of lifelong plastic consumption.