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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Food & Water Gut & Microbiome Human Health Effects Nanoplastics Sign in to save

Impact of Nanoplastic Particles on Macrophage Inflammation and Intestinal Health in a Mouse Model of Inflammatory Bowel Disease

Nanomaterials 2024 8 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Marlene Schwarzfischer, Tano S. Ruoss, Anna Niechcial, Sung Sik Lee, Marcin Wawrzyniak, Andrea Laimbacher, Kirstin Atrott, Roberto Manzini, Marijn Wilmink, Luise Linzmeier, Yasser Morsy, Silvia Lang, Gerhard Rogler, Rälf Kaegi, Michael Scharl, Marianne R. Spalinger

Summary

Researchers studied the effects of nanoplastic ingestion in a mouse model of inflammatory bowel disease and found that the particles influenced macrophage inflammation and intestinal health. The findings offer some reassurance that typical levels of nanoplastic exposure may not dramatically worsen bowel disease symptoms. However, the study notes that individuals with higher plastic intake due to lifestyle or dietary habits could face different long-term gastrointestinal risks.

Body Systems
Digestive Immune
Models
Human Mouse

Our findings from animal models offer some reassurance to IBD patients regarding the effects of NP ingestion. However, variations in lifestyle and dietary habits may lead to significantly higher plastic intake in certain individuals, raising concerns about potential long-term gastrointestinal effects of lifelong plastic consumption.

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