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Microplastic in Gastric Fasting Liquid and Associated Gastric Pathology
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This study found microplastic particles in gastric fluid samples collected from patients undergoing routine stomach examinations, and noted associations between microplastic presence and gastric pathologies including H. pylori infection, intestinal metaplasia, and inflammation. The findings provide direct clinical evidence that microplastics accumulate in the human stomach and may be linked to gastric disease, though causality is not yet established. This is an important step toward understanding whether microplastic ingestion contributes to gastrointestinal health problems in humans.
H. pylori, Intestinal metaplasia, Inflammation, Microplastic, Plastic, Sydney classification.
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Suspected Microplastic-like Particles in Human Gastric Autopsy Samples: An Exploratory Histopathological and Biochemical Study
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Scientists examined stomach tissue samples from 55 autopsies and found tiny plastic-like particles in about 1 out of 4 cases. Every person with these particles also had stomach inflammation, compared to only about a third of those without particles, suggesting a possible link between microplastics and digestive tissue damage. That said, this is a small, exploratory study, so more research is needed before we know if microplastics actually cause this inflammation or are just present alongside it.
Polyethylene microplastics cooperate with Helicobacter pylori to promote gastric injury and inflammation in mice
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Researchers investigated how polyethylene microplastics interact with the stomach bacterium Helicobacter pylori in mice. They found that H. pylori formed biofilms on microplastic surfaces, and that mice exposed to both microplastics and the bacteria developed more severe gastric inflammation than those exposed to either alone. The study suggests that microplastics may facilitate bacterial colonization in the stomach and amplify infection-related tissue damage.
Microplastics in the Gastrointestinal Tract: A Systematic Review
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This systematic review summarizes research on microplastics found in the human gastrointestinal tract. It highlights that microplastics are accumulating in our digestive systems through food and water, and calls for urgent research to understand how these particles may affect gut health and overall well-being.
Micro- and nanoplastics in gastric cancer: A narrative review
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This review summarizes existing lab research on tiny plastic particles and stomach cancer. Studies in cell and 3D tissue models suggest these particles may trigger cell damage, inflammation, and altered signaling linked to cancer growth, and may interact with the bacteria H. pylori, but a direct cause of stomach cancer in humans has not been established.
The infiltration of microplastics in human systems: Gastrointestinal accumulation and pathogenic impacts
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This review focuses on how microplastics accumulate in the human digestive system and what health problems they might cause. The authors explain that people ingest microplastics through food, water, and air, and these particles may trigger inflammation, disrupt gut bacteria, and potentially contribute to gastrointestinal diseases.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.