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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Human Health Effects
Nanoplastics
Reproductive & Development
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Polystyrene nanoplastic exposure actives ferroptosis by oxidative stress-induced lipid peroxidation in porcine oocytes during maturation
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
2024
27 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 65
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Yijing He,
Yijing He,
Qiao Li,
Tianhang Yu,
Tianhang Yu,
Qinfeng Sun,
Heran Li,
Qinfeng Sun,
Heran Li,
Yiyi Lin,
Qinfeng Sun,
Qinfeng Sun,
Tianhang Yu,
Miaoyu Chen,
Tianhang Yu,
Yiyi Lin,
Miaoyu Chen,
Yiyi Lin,
Jianjun Dai,
Weihan Wang,
Weihan Wang,
Qiao Li,
Shiqiang Ju
Shiqiang Ju
Summary
Researchers found that polystyrene nanoplastics trigger ferroptosis — a form of iron-dependent cell death driven by fat oxidation — in pig egg cells, disrupting their maturation and reproductive viability. This finding raises concerns about nanoplastic exposure potentially impairing fertility by damaging the eggs needed for reproduction.
In conclusion, PS-NPs caused ferroptosis in porcine oocytes by increasing oxidative stress and altering lipid metabolism, leading to the failure of oocyte maturation.
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