0
Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Nanoplastics Reproductive & Development Sign in to save

Polystyrene nanoplastic exposure actives ferroptosis by oxidative stress-induced lipid peroxidation in porcine oocytes during maturation

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2024 27 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Yijing He, Tianhang Yu, Heran Li, Qinfeng Sun, Miaoyu Chen, Yiyi Lin, Yiyi Lin, Jianjun Dai, Weihan Wang, Qiao Li, Shiqiang Ju

Summary

Researchers found that polystyrene nanoplastics trigger ferroptosis — a form of iron-dependent cell death driven by fat oxidation — in pig egg cells, disrupting their maturation and reproductive viability. This finding raises concerns about nanoplastic exposure potentially impairing fertility by damaging the eggs needed for reproduction.

Polymers
Body Systems

In conclusion, PS-NPs caused ferroptosis in porcine oocytes by increasing oxidative stress and altering lipid metabolism, leading to the failure of oocyte maturation.

Share this paper