Microplastic and associated emerging contaminants in marine fish from the South China Sea: Exposure and human risks

Microplastics can act as vectors of chemical contaminants in aquatic environments, but the extent to which this phenomenon contributes to chemical exposure in marine organisms remains poorly understood. We investigated the occurrence of microplastics and emerging contaminants (ECs), including antibiotics and per- and polyfluoroalkyl substances (PFAS) in 14 marine fish species. Microplastics were detected in all marine fish species, mainly in the gastrointestinal tract. Fluoroquinolones and tetracyclines were the dominant antibiotics in fish muscles with maximum concentrations of 24.84 and 26.95 ng g ww, while perfluorooctanesulfonic acid (PFOS, 0.039-0.95 ng g ww) was the dominant component in the PFAS profile. Fish with more microplastics had significantly higher concentrations of fluoroquinolones and perfluoroalkyl acids than fish with less microplastics (p < 0.05), but the correlation was not observed in other chemicals. Structural equation modeling revealed the contribution of microplastics in fish on the level of ECs contamination. The health quotient value indicated the low health risk of single compounds via fish consumption to humans; however, the combined risk of microplastics and ECs still needs to be considered. This work highlights the link between microplastics with associated ECs ingested by aquatic organisms and the human health risk of consuming polluted seafood.