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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Marine & Wildlife Nanoplastics Reproductive & Development Sign in to save

Exposure to Nanoplastics Cause Caudal Vein Plexus Damage and Hematopoietic Dysfunction by Oxidative Stress Response in Zebrafish (Danio rerio)

International Journal of Nanomedicine 2024 4 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Juntao Chen, Chunjiao Lu, Wenjie Xie, Xiaoqian Cao, Jiannan Zhang, Juanjuan Luo, Juan Li

Summary

Researchers found that nanoplastic exposure in zebrafish embryos caused damage to blood vessel development and impaired the formation of blood cells. The nanoplastics triggered oxidative stress in vascular and blood-forming cells, disrupting normal developmental processes. The study suggests that nanoplastic contamination in aquatic environments could affect early development in fish by interfering with their circulatory and blood cell production systems.

The results of this study suggest that NPs induce oxidative stress in vascular ECs and HSPCs, which mediates CVP damage and impairs hematopoiesis in zebrafish embryos.

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