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First evidence of molecular response of the shrimp Hippolyte inermis to biodegradable microplastics

Journal of Hazardous Materials 2024 2 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Amalia Amato, Roberta Esposito, Bruno Pinto, Bruno Pinto, Thomas Viel, Francesca Glaviano, Mariacristina Cocca, Loredana Manfra, Giovanni Libralato, Eliahu D. Aflalo, Amir Sagi, Maria Costantini, Valerio Zupo

Summary

Researchers provided the first molecular evidence of how the Mediterranean shrimp Hippolyte inermis responds to biodegradable microplastics at the gene expression level. Larvae were exposed to five different biodegradable polymers at varying concentrations, and researchers measured changes in 18 genes involved in stress response and detoxification. The study establishes this shrimp species as a model organism for studying the biological effects of biodegradable plastics on marine crustaceans.

Polymers

The increasing demand for sustainable alternatives to conventional plastics has propelled the interest in bioplastics. A few papers reported on the effects of plastics on crustaceans, but no indication about biodegradable polymers is available. Hippolyte inermis Leach, 1816 is a protandric shrimp commonly living on leaves of the seagrass Posidonia oceanica, in the Mediterranean Sea. This crustacean is typically chosen as a model to study sex differentiation processes. Here, we demonstrated its convenience as a model organism to study the effects of biodegradable polymers (BPs). Five BPs were studied: polybutylene succinate (PBS), polybutylene succinate-co-butylene adipate (PBSA), polycaprolactone (PCL), poly-3-hydroxybutyrates (PHB) and polylactic acid (PLA). Larvae of H. inermis were exposed to three concentrations of each BP (1, 5 and 10 mg/L, respectively) for ten days. After exposure, the expression levels of eighteen genes involved in stress response and detoxification processes, retrieved from a H. inermis transcriptomic library, were validated by Real Time qPCR. This study is the first using a molecular approach to detect H. inermis responses to contaminants and in particular to biodegradable polymers, through the evaluation of functional gene's pathways.

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