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Effects of Particle Size and Charges in Modulating the Molecular and Cellular Responses of Polystyrene Nanoplastics to Serum Albumin

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Polymers

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Article Tier 2

Cellular Uptake and Nuclear Accumulation of Polystyrene Nanoplastics in 3T3 Fibroblasts and Hepatocytes of Rattus norvegicus

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Scientists found that tiny plastic particles called nanoplastics can get inside liver and connective tissue cells from rats, and even sneak into the cell's nucleus, where DNA is stored. Cells exposed to these plastics showed signs of stress and damage, including swelling and higher rates of cell death, suggesting these ultra-small plastic particles may be more harmful than previously thought. While this study used animal cells rather than human cells, it raises important questions about what everyday exposure to nanoplastics (found in food packaging, water, and other sources) might mean for our own cellular health.

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