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Analytical techniques for assessing microplastic-induced physiological damage in tissues
Summary
This study reviewed advanced analytical techniques—including FTIR, Raman spectroscopy, electron microscopy, and biochemical assays—for identifying and visualizing microplastics in biological tissues, finding that multi-method approaches yield the most comprehensive characterization of tissue damage.
Microplastic contamination is a growing environmental concern with potential health risks. This study aims to investigate the physiological effects of microplastics and develop strategies to mitigate their impact. The research utilizes advanced analytical techniques to identify, visualize, and characterize microplastics in tissues. Methods such as FTIR and Raman spectroscopy, X-ray Micro-CT, CLSM, LM, TEM, SEM, Fluorescence Microscopy, IHC, and biochemical assays are employed. The findings reveal that microplastics can induce oxidative stress, inflammation, and cellular damage, which may lead to various pathologies. The implications of this research lie in understanding the complex mechanisms underlying microplastic toxicity and developing effective environmental and public health policies. Standardizing protocols and establishing dose-response relationships are suggested for future research. Overall, this study contributes to the comprehension of analytical techniques to analyse microplastic-induced physiological damage and its implications for human health.