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Novel biocatalyst for sustainable plastic removal

Zenodo (CERN European Organization for Nuclear Research) 2026
Paula Vidal Ramon, Ana Robles Martín, Laura Fernández-López, José Luis González Alfonso, David Almendral Nieto, Rubén Muñoz Tafalla, Francisco J. Plou, Vı́ctor Guallar, Keiji Numata, Manuel Ferrer

Summary

This is a duplicate entry for the same metagenomic PET-degrading enzyme paper as ID 1755, describing the characterization of LipMRD9 as a novel biocatalyst for breaking down PET plastics. Duplicate entry; the core finding is that this enzyme offers a biodegradable pathway for plastic waste, potentially reducing microplastic generation at the source.

Polymers
PE PET

Plastic pollution, particularly from polyethylene terephthalate (PET), represents one of the most pressing global environmental challenges of our time. PET, widely used in packaging and textiles, is resistant to natural degradation, contributing significantly to microplastic accumulation in ecosystems. Recent advances in metagenomics have enabled the discovery of novel PET-degrading enzymes, while computational and experimental techniques have been instrumental in identifying key residues that enhance catalytic efficiency and substrate specificity. In this work, we present the characterization of PETase activity in the metagenomic lipase LipMRD9, which demonstrates significant potential for PET biodegradation.

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