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Comparison of lung disorders following intratracheal instillation of polystyrene microplastics with different surface functional groups
Summary
Intratracheal instillation of polystyrene microplastics with different surface functional groups (plain, carboxylated, aminated) in rats showed low pulmonary toxicity overall, but surface chemistry influenced acute-phase inflammatory responses—suggesting surface functionalization is an important variable in microplastic respiratory toxicity assessment.
These results suggest that these polystyrenes do not have high pulmonary toxicity, although there are differences in toxicity due to differences in surface functional groups only in the acute phase.
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