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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Gut & Microbiome
Human Health Effects
Nanoplastics
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Effect of disruption in the intestinal barrier function during the transgenerational process on nanoplastic toxicity induction in Caenorhabditis elegans
Environmental Science Nano
2025
9 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Yuxing Wang,
Dayong Wang
Summary
This study found that nanoplastics can cause toxic effects that pass from parents to offspring across generations in tiny roundworms. The damage was linked to disruption of the intestinal barrier, which normally protects against harmful substances. These findings raise concerns that nanoplastic exposure could have long-lasting health effects beyond a single generation.
Models
After exposure at the parental generation (P0-G), nanoplastics can induce transgenerational toxicity.