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Effect of disruption in the intestinal barrier function during the transgenerational process on nanoplastic toxicity induction in <i>Caenorhabditis elegans</i>

Environmental Science Nano 2025 9 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 63 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Dayong Wang, Yuxing Wang

Summary

This study found that nanoplastics can cause toxic effects that pass from parents to offspring across generations in tiny roundworms. The damage was linked to disruption of the intestinal barrier, which normally protects against harmful substances. These findings raise concerns that nanoplastic exposure could have long-lasting health effects beyond a single generation.

Models

C elegans

After exposure at the parental generation (P0-G), nanoplastics can induce transgenerational toxicity.

Effect of disruption in the intestinal barrier function during the transgenerational process on nanoplastic toxicity induction in <i>Caenorhabditis elegans</i>

Summary

Discussion