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Article Tier 2 Human Health Effects Marine & Wildlife Nanoplastics Sign in to save

Author response for "Interactive toxicity effects of metronidazole, diclofenac, ibuprofen, and differently functionalized nanoplastics on marine algae Chlorella variabilis"

2025

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Interactive toxicity effects of metronidazole, diclofenac, ibuprofen, and differently functionalized nanoplastics on marine algae Chlorella sp.

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Researchers examined the combined toxicity of common pharmaceutical drugs and nanoplastics with different surface coatings on marine algae. They found that the interaction between drugs and nanoplastics produced effects ranging from additive to synergistic, depending on the specific combination, with amine-coated nanoplastics generally causing more harm. The study highlights that real-world mixtures of pharmaceutical and plastic pollutants in oceans may pose greater risks to marine life than either contaminant alone.

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Interactive effects of selected pharmaceutical products (metronidazole, diclofenac, ibuprofen) and differently functionalized nanoplastics on marine algae Chlorella sp.

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The combined toxicity of three pharmaceutical products (metronidazole, diclofenac, ibuprofen) and polystyrene nanoplastics with different surface functionalization (NH2 and COOH) was tested on marine algae Chlorella sp. Polystyrene nanoplastics at 1 mg/L caused substantial growth inhibition, while combining pharmaceuticals with nanoplastics reduced rather than amplified toxicity.

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The influence of microplastics on the toxic effects and biodegradation of bisphenol A in the microalgae Chlorella pyrenoidosa

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Researchers discovered that polystyrene microplastics worsen the toxic effects of the common chemical bisphenol A (BPA) on green algae, suggesting that microplastics in aquatic environments can amplify the harm caused by other pollutants and may have cascading effects on aquatic food chains.

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Physiological, morphological, and growth effects of microplastics on freshwater alga Chlorella vulgaris

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Researchers showed that microplastics inhibit growth, reduce chlorophyll and photosynthetic efficiency, and trigger oxidative stress in the freshwater alga Chlorella vulgaris in a concentration-dependent manner, suggesting the species could serve as a bioindicator for aquatic microplastic contamination.

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Nanoplastic exposure inhibits growth, photosynthetic pigment synthesis and oxidative enzymes in microalgae: A new threat to primary producers in aquatic environment

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Scientists found that tiny plastic particles (nanoplastics) can seriously harm microalgae, the tiny plants that form the base of the ocean's food chain, by slowing their growth by up to 42%, reducing their ability to photosynthesize, and triggering stress damage inside their cells. Since these algae are eaten by small creatures that are eaten by bigger fish (eventually including the seafood we eat), this damage could ripple up the food chain and disrupt entire aquatic ecosystems. While this study looked at algae rather than humans directly, it adds to growing evidence that nanoplastic pollution, now found

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