Exposure routes induce differential intestinal damage in zebrafish from polystyrene microplastics

Acute Effects of Size Dependent Low-Density Polyethylene Microplastics on Zebrafish

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Zebrafish embryos exposed to low-density polyethylene microplastics for 48 hours accumulated particles in their gut, experienced reduced hatching rates, increased heart rates, and significant tissue damage, with smaller particles causing the most harm. These acute effects in a widely used model organism suggest that even brief early-life exposure to plastic particles can disrupt normal development.

Gauging the effects of a chronic exposure to polystyrene nanoplastics in the liver and intestine of Carassius auratus

Oxidative damage and intestinal microbial imbalance induced by polystyrene microplastics and cadmium in zebrafish (Danio rerio)

Polystyrene microplastics: environmental presence, pathways, and biological impact

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Researchers reviewed the environmental presence, transport pathways, and biological impacts of polystyrene microplastics, documenting how widespread food packaging use leads to pervasive contamination of aquatic and terrestrial ecosystems and raises concerns for organismal and human health.

Recent advances of microplastics toxicity and fate on zebrafish-a review

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This review synthesizes evidence on how micro- and nanoplastics cause developmental, reproductive, gastrointestinal, and oxidative stress toxicity in zebrafish, positioning the species as a valuable vertebrate model for understanding plastic pollutant effects across trophic levels. Zebrafish research is accelerating mechanistic understanding of how microplastics harm vertebrate biology, providing insights relevant to assessing risks for fish-eating wildlife and humans.