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The Impact of Microplastics and Nanoplastics on Health and Reproductive Outcomes
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This scoping review compiled existing literature on micro- and nanoplastic exposure in relation to women's health and reproductive outcomes. The study identified inverse associations between microplastic exposure and adverse neonatal outcomes such as low birth weight, and highlighted physiological routes of absorption and vulnerable organs, while noting significant gaps in current knowledge that need to be addressed.
Inverse associations between Micro/Nano Plastics (MNP) exposure and adverse neonatal outcomes (e.g. low birth weight) have been found. Associated health conditions and outcomes have been postulated. Physiological routes of MNP absorption and susceptible organs to the toxicity of MNP have been proposed. An overarching synthesis and compilation of existing literature on the topic of MNP exposure with women has not yet been conducted. To identify gaps in knowledge and combine suggested correlations between health outcomes and sub-population vulnerability a scoping review will be done.
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Exposure to micro- and nanoplastics and human reproductive outcomes: a systematic review
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This systematic review summarizes existing research on whether micro and nanoplastics affect human fertility and pregnancy outcomes. While the evidence is still emerging, the review found that these particles have been detected in placenta and fetal tissue, raising important questions about potential effects on reproductive health that warrant further study.
The effects of exposure to microplastics on female reproductive health and pregnancy outcomes: A systematic review and meta-analysis
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This meta-analysis pools data from multiple studies to assess how microplastic exposure affects female reproductive health and pregnancy outcomes. The findings suggest that microplastic accumulation may be linked to adverse effects on fertility and pregnancy, highlighting an important and underexplored area of concern for women's health.
Understanding the impact of nanoplastics on reproductive health: Exposure pathways, mechanisms, and implications
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This review summarizes existing research on how nanoplastics (tiny plastic particles smaller than one micrometer) affect reproductive health in animals and potentially humans. Studies show that nanoplastics can accumulate in reproductive organs including the placenta, and evidence from animal studies links exposure to hormone disruption, reduced fertility, and developmental problems. The authors highlight a significant knowledge gap about nanoplastic effects on human reproduction, despite growing evidence that these particles reach our reproductive systems.
Microplastics exposure during perinatal period: Impacts on neonatal immune and metabolic programming - a scoping review
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This scoping review synthesizes research on microplastic exposure during the perinatal period and its potential impacts on neonatal immune and metabolic development. Researchers evaluated mechanisms of immune and metabolic disruption, size- and dose-dependent effects, and the exposure pathways that may influence newborn health outcomes. The study highlights that the developing fetus and newborn may be particularly vulnerable to micro- and nanoplastic exposure.
Evidence Status and Assessment Challenges of Microplastic Exposure on Neonatal Health Outcomes
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This review summarizes existing research on microplastics found in the placenta, amniotic fluid, umbilical cord blood, breast milk and meconium. Observational studies link microplastic pollution to lower birth weight and shorter pregnancies, while experimental studies report oxidative stress and inflammation in offspring, though data remain limited and inconsistent.
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