We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Comprehensive Organ-specific Assessment of Biomarkers, Histopathological Alterations, Bioaccumulation and Genotoxicity Responses of Mozambique tilapia (Oreochromis mossambicus) exposed to Polyvinyl chloride Microplastics.
AI summary Read the abstract
Juvenile tilapia fish were exposed to PVC microplastics in water for 14 days, with the particles building up most in gills, then gut, liver and muscle. Exposure caused oxidative stress, liver enzyme changes, blood cell abnormalities, chromosomal damage and gill tissue injury, with effects worsening at higher concentrations.
Freshwater ecosystems are increasingly at risk from microplastic contamination. However, information on the sub-lethal toxicity of polymer-specific microplastics in freshwater fish remains limited. The current study assessed the toxicological effects of polyvinyl chloride microplastics (PVC-MPs) with a particle size range 1 to 2500 μm in juvenile Oreochromis mossambicus under controlled laboratory conditions. A 96-h median lethal concentration (LC50) of 90.2 mg/L (95% CI) was determined, and O. mossambicus were subsequently exposed to three sub-lethal concentrations (7.05, 15.63, and 40.04 mg/L) for 14 days. Following exposure, fish were euthanized to determine PVC-MPs accumulation in gill, gut, liver, and muscle. PVC-MPs accumulated in a concentration-dependent manner, with tissue-specific bioaccumulation following the order gill > gut > liver > muscle. PVC-MPs exposure significantly altered the Oxidative stress biomarkers such as superoxide dismutase (SOD), catalase (CAT), thiobarbituric acid reactive substances (TBARS), glutathione (GSH), and hepatic biomarkers, alanine aminotransferase (ALT) and alkaline phosphatase (ALP). Alteration in proximate composition (total protein, total carbohydrates and total lipids) indicated disturbance in energy metabolism. Hematological analysis revealed significant reduction in erythrocyte related indices accompanied by elevated leukocyte counts, while genotoxicity assessment showed significant increase in micronucleus frequency, demonstrating chromosomal damage. Histopathological analysis further revealed progressive epithelial lifting, hyperplasia, lamellar fusion, interlamellar cell mass alteration and erythrocyte aggregation, with lesion severity increasing with exposure concentration. Collectively, these findings demonstrate that sublethal PVC-MPs exposure induces tissue-specific bioaccumulation, oxidative stress, metabolic dysfunction, hematological alterations, genotoxicity and gill pathology in juvenile O. mossambicus, highlighting the ecological risks of PVC-MPs in freshwater ecosystems.
More Papers Like This
Ingestion of Polyvinylchloride Powder Particles Induces Oxidative Stress and Hepatic Histopathological Changes in Oreochromis niloticus (Nile Tilapia)—A Preliminary Study
AI summary Read the abstract
Researchers found that oral exposure to PVC microplastic powder induced oxidative stress and liver histopathological changes in Nile tilapia, with altered water quality parameters and tissue damage indicating significant toxicological effects from ingested plastic particles.
Integrated Biomarker, Histopathological and Genotoxicity‐Based Toxicological Evaluation of Polystyrene and Polyethylene Microplastics in Oreochromis mossambicus
AI summary Read the abstract
Researchers exposed Mozambique tilapia to polystyrene and polyethylene microplastics and found dose-dependent accumulation in gill, gut, and liver tissues. Polyethylene proved significantly more toxic, causing greater oxidative stress, metabolic disruption, and chromosomal damage as measured by micronucleus assays. The study provides evidence that different polymer types can have markedly different toxicological impacts on freshwater fish.
Subacute toxic effects of polyvinyl chloride microplastics (PVC-MPs) in juvenile common carp, Cyprinus carpio (Pisces: Cyprinidae)
AI summary Read the abstract
Juvenile common carp exposed to polyvinyl chloride microplastics showed dose-dependent toxic effects including tissue damage, oxidative stress, and altered biochemical markers over a subacute exposure period. The results indicate that PVC microplastics are harmful to freshwater fish at ecologically relevant concentrations.
Biochemical, Genotoxic and Histological Implications of Polypropylene Microplastics on Freshwater Fish Oreochromis mossambicus: An Aquatic Eco-Toxicological Assessment
AI summary Read the abstract
Researchers fed polypropylene microplastics to freshwater tilapia and found they caused oxidative stress, DNA damage, and liver tissue deterioration, with more severe effects after 14 days compared to acute 96-hour exposure. The microplastics disrupted antioxidant enzyme systems and neurotransmitter activity in the fish. The study demonstrates that prolonged microplastic ingestion poses a significant ecological threat to freshwater fish species.
Assessment of dietary polyvinylchloride, polypropylene and polyethylene terephthalate exposure in Nile tilapia, Oreochromis niloticus: Bioaccumulation, and effects on behaviour, growth, hematology and histology
AI summary Read the abstract
Nile tilapia fish fed three common types of microplastics (PVC, polypropylene, and PET) showed reduced growth, abnormal behavior, blood cell damage, and tissue damage in their gills, liver, and intestines. The harmful effects increased with higher doses of microplastics and varied by plastic type. Since tilapia is one of the most widely consumed fish globally, these findings raise concerns about the health of fish that may carry microplastic contamination to human diets.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.