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Surface charge-dependent toxicity of polystyrene nanoplastics in Microcystis aeruginosa: Growth suppression, physiological alterations and transcriptomic mechanisms
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Researchers examined the molecular mechanisms by which polystyrene nanoplastics affect Pseudomonas aeruginosa, finding dose-dependent responses in growth, metabolism, and virulence gene expression that reveal how nanoplastics interact with environmentally relevant bacteria.
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Exposure of Saccharomyces cerevisiae to three polystyrene nanoplastic variants (unmodified, carboxylated, aminated) paradoxically promoted yeast growth while simultaneously elevating oxidative stress biomarkers including ROS, MDA, and SOD, with aminated nanoplastics showing the greatest toxicity at all concentrations tested. The findings demonstrate that surface chemistry — not just concentration — determines nanoplastic toxicity, a key insight for modeling ecological and human health risks from nanoplastic pollution.
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