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Microplastics: An Emerging Carcinogen in the Human Body

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This review paper summarizes existing research on microplastics entering the human body through skin, nose, and mouth, with particles detected in faeces, blood, lungs, and placenta. The reviewed studies report that microplastics disrupt cell functions, inflammation, and other processes linked to toxicity and cancer development.

Microplastic (MP) contamination is a significant environmental issue that poses a threat to human health. There is a notable increase in the emissions of these particles yearly. MPs enter the human body through skin, nose, and mouth, and can be found in faeces, circulation, lower respiratory tract, and placenta. Exposure to MPs disrupts cellular epigenetic controls, inflammatory responses, redox reactions and homeostasis. MP-induced toxicity and genotoxicity cause the formation of cancer and various chronic diseases. This section discusses current toxicological findings and causal effect mechanisms in detail to reveal the relationship between microplastics and human health and tumorigenesis.

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