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Endocrine disruptors and their Agadatantra perceptions
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This review paper discusses chemicals called endocrine disruptors, which come from sources like plastics, pesticides, and cosmetics and can affect hormones, reproduction, and other body systems. It compares modern scientific understanding of these substances with concepts from Ayurveda, a traditional Indian medicine system, that describe similar ideas about low-level toxin exposure.
Endocrine disruptors are exogenous substances that interfere with the normal functioning of the endocrine system and lead to adverse developmental, reproductive, neurological, metabolic, and immunological effects in humans and animals. In recent decades, industrialization, pesticide use, plastic pollution, cosmetic chemicals, and food contaminants have increased human exposure to endocrine-disrupting chemicals (EDCs). Modern toxicology recognizes them as significant environmental health hazards. Ayurveda, particularly the branch of Agadatantra, provides a unique perspective on chronic low-dose toxicity through concepts such as Gara Visha, Dushi Visha, Viruddha Ahara, and environmental contamination. This article explores endocrine disruptors from both modern scientific and Ayurvedic viewpoints and correlates their toxicodynamic actions with Agadatantra principles.
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This review investigated the potential of microplastics to alter human hormone signaling, synthesizing evidence that plastic particles and their chemical additives can act as endocrine disruptors at environmentally relevant concentrations. The paper highlighted reproductive and metabolic pathways as areas of particular concern.
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This review pulls together existing research on "endocrine disruptors", chemicals found in everyday products (including micro- and nanoplastics) that can interfere with hormones, and how they affect children, who are especially vulnerable because their bodies and brains are still rapidly developing. The research suggests these chemicals may disrupt growth, brain development, and puberty, and some effects might even be passed down to future generations, though more studies are still needed to fully confirm this. The takeaway: since these chemicals are nearly impossible to completely avoid, understanding and reducing exposure during pregnancy and childhood could matter for long-term health.
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