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Article Tier 2 Human Health Effects Reproductive & Development Sign in to save

Microplastic exposure in daily life and the risk of pregnancy-induced hypertension: A study on the association between environmental pollutants and maternal-fetal health outcomes

Journal of Hazardous Materials 2025 8 citations

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In a study of pregnant women, those with pregnancy-induced high blood pressure had 1.46 times more microplastics in their umbilical cords than healthy pregnant women, with polyethylene and polycarbonate being especially elevated. Microplastic exposure was linked to use of plastic containers and takeout meals, and higher levels were associated with worse outcomes for newborns. While this preliminary study has limitations, it suggests that everyday microplastic exposure during pregnancy may be connected to dangerous blood pressure complications.

Polymers
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Pregnancy-induced hypertension (PIH) is a significant threat to maternal and fetal health. Current prevention and treatment strategies for PIH are limited due to inadequate understanding of its etiology and risk factors. This study investigates the link between maternal microplastic (MP) exposure and PIH incidence, using questionnaires, umbilical cord sampling, microplastic detection, and statistical analysis to assess the impact of lifestyle factors on PIH risk. We found higher concentrations of polyethylene (PE) and polycarbonate (PC) in the umbilical cords of PIH patients (*P < 0.05). Total MP levels were 1.46 times higher in the PIH cases. Factors like plastic tableware, seafood intake, and plastic-packaged beverages were potential risk factors, but not independent in multivariate analysis (P > 0.05). MP exposure correlated with plastic containers and takeout meals (*P < 0.05) and was associated with increased neonatal mortality and lower Apgar scores (*P < 0.05). These findings suggest that MPs could be a potential chemical marker for PIH risk. However, the results should be interpreted with caution due to the limitations of sample size and methodology. In conclusion, our preliminary study highlights the link between maternal MP exposure and PIH incidence. Future research should explore MP exposure and long-term health effects to improve pregnancy management and reduce PIH incidence.

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