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25 nm AuPS Pristine and Weathered Characterization and Triculture Tox
Summary
Scientists tested how tiny plastic particles (nanoplastics) behave in a lab model of the human gut lining, comparing fresh plastic particles to ones that had been "weathered" by UV light—similar to what happens when plastic breaks down in sunlight outdoors. This matters because it helps researchers understand whether sunlight-damaged microplastics—which are common in our environment and food—might be absorbed differently by our intestines or cause different effects than fresh plastic particles, giving us better tools to study real-world plastic exposure risks.
Physicochemical Characterization and Toxicity in a triculture transwell small intestinal epithelial model for pristine and UV-aged gold core-polystyrene shell (AuPS) nanoparticles, as published in Majumder et al., Impact of UV Aging on the Toxicity and Bioavailability of Inductively Coupled Plasma Mass Spectrometry (ICP-MS)-Traceable Core-Shell Polystyrene Nanoplastics in an In Vitro Triculture Small Intestinal Epithelium Model, 2025, Toxics. PMID: 41304491 PMCID: PMC12656232 DOI: 10.3390/toxics13110939