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Marine microplastic concentration and associations with stroke and chronic disease prevalence

npj Cardiovascular Health 2026 1 citation ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Sai Rahul Ponnana, El-Hussain Shamsa, Zhuo Chen, T. G. Rajagopalan, Tong Zhang, Santosh Sirasapalli, Skanda Moorthy, Jean-Eudes Dazard, Sadeer Al-Kindi, Salil V. Deo

Summary

A new study found that coastal areas with higher levels of microplastics (tiny plastic particles) in nearby ocean water also had higher rates of stroke, diabetes, and high blood pressure. While this doesn't prove microplastics directly cause these health problems, it's an early warning sign worth paying attention to, especially since stroke stood out as one of the strongest patterns in the data. More research is needed to understand if and how microplastic exposure might affect our health.

Models

Microplastics (MPs), synthetic polymer particles <5 mm, are emerging environmental contaminants with potential cardiometabolic relevance. We conducted a cross-sectional analysis of 709 coastal census tracts ( < 200 meters from shoreline) by linking NOAA marine microplastic measurements with chronic disease prevalence estimates from the CDC PLACES database. A total of 154 demographic, socioeconomic, and environmental variables including age, sex, race, median household income, Social Vulnerability Index, insurance coverage, and PM2.5 were incorporated to adjust for confounding. Adjusted Poisson regression models showed that tracts with the highest microplastic exposure had higher prevalence of stroke (PR = 1.21, 95% CI: 1.13-1.29), diabetes (PR = 1.17, 95% CI: 1.10-1.24), and hypertension (PR = 1.10, 95% CI: 1.06-1.14) compared with low-exposure areas. Among all covariates, XGBoost models with SHAP interpretation identified microplastic concentration as an important environmental predictor of stroke prevalence. These ecological findings suggest microplastics were associated with chronic disease patterns and warrant further investigation.

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