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Correction to “Combined Exposure of Nano‐Titanium Dioxide and Polystyrene Nanoplastics Exacerbate Oxidative Stress‐Induced Liver Injury in Mice by Regulating the Keap‐1/Nrf2/ARE Pathway”
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This notice is simply a correction to a previously published study, the authors fixed a mislabeled image but confirm all original findings and conclusions still stand. The underlying research found that combined exposure to nano-titanium dioxide (a common ingredient in sunscreens and food products) and nanoplastics caused more liver damage in mice than either substance alone, by triggering harmful oxidative stress. This matters because it suggests everyday exposure to multiple types of nanoparticles together, rather than just one at a time, could pose greater risks to liver health than previously understood.
T. Jia, P. Nie, and H. Xu, “Combined Exposure of Nano-Titanium Dioxide and Polystyrene Nanoplastics Exacerbate Oxidative Stress-Induced Liver Injury in Mice by Regulating the Keap-1/Nrf2/ARE Pathway,” Environmental Toxicology 39, no. 5 (2024): 2681–2691, https://doi.org/10.1002/tox.24141. In Figure 4G, due to an oversight during the final stages of image arrangement and typesetting, there was a misuse of the image that occurred in the NAC+NaP+TiO2 NP group (400×). The figure has now been corrected below, and the authors have provided the original images. The authors confirm that all the experimental results and corresponding conclusions mentioned in the article remain unaffected. FIGURE 4. The biochemical indicators after intraperitoneal injection of N-Acetyl-L-cysteine (NAC). (A–C) The body weight, liver weight, and liver coefficient of mice after 28-day gavage. (D) AKP, (E) ALT, and (F) AST enzyme activities in the liver. (G) Representative histological images of the liver following 28-day gavage, red circle represents infiltration of inflammatory cell, black circle represents cellular vacuoles and the yellow asterisk represents apoptosis (×200 and ×400; hematoxylin and eosin). Data represented as means ± SD. *p < 0.05, **p < 0.01. We apologize for this error.
More Papers Like This
Combined exposure of nano‐titanium dioxide and polystyrene nanoplastics exacerbate oxidative stress‐induced liver injury in mice by regulating the Keap‐1 / Nrf2 / ARE pathway
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Researchers found that mice exposed to both polystyrene nanoplastics and nano-titanium dioxide together suffered worse liver damage than those exposed to either substance alone. The combined exposure amplified oxidative stress and disrupted a key protective signaling pathway in the liver, suggesting that co-exposure to multiple nanoparticles may pose greater health risks than individual exposures.
Correction: Šoša et al. Metabolic Dysfunction-Associated Steatotic Liver Disease Induced by Microplastics: An Endpoint in the Liver–Eye Axis. Int. J. Mol. Sci. 2025, 26, 2837
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This is a correction notice for an earlier paper, not new research, it fixes errors in a study that explored how microplastics might contribute to fatty liver disease and potentially affect eye health too. Since the original findings haven't changed in substance, the key takeaway remains the same: there's early evidence that microplastic exposure could play a role in liver damage, which is worth watching as scientists learn more about how these tiny plastic particles affect our bodies.
Oxidative stress response biomarkers in gills and liver of bullfrog tadpoles semi-chronically exposed to combined microplastics and titanium dioxide nanoparticles
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Scientists exposed tadpoles to microplastics and titanium dioxide nanoparticles (common in sunscreens and food coloring) and found the combo caused more cell damage and stress than either pollutant alone, particularly harming liver function and energy metabolism. While this study was done in frogs, not humans, it's a warning sign: these same pollutants are widespread in our water and food, and we're typically exposed to them as mixtures, not one at a time—meaning their combined health effects on us may also be worse than tests on individual substances suggest.
Correction: Jani, V.; Wu, S. Nanoplastics (NPs): Environmental Presence, Ecological Implications, and Mitigation Approaches. Microplastics 2025, 4, 48
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This is a correction notice, not a new study—the authors fixed a few incorrect references in their original review paper about tiny plastic particles called nanoplastics, which are found in the environment and can affect ecosystems and potentially human health. The science itself hasn't changed; this update just ensures the sources backing up the original findings are accurate. If you're interested in what nanoplastics mean for your health, the original 2025 review article is still the one to check out.
Correction: Plastisphere-isolated Stutzerimonas balearica SP-H sustains stable sulfur-autotrophic denitrification under microplastic stress
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This is simply a correction notice fixing a figure error in a previously published study, it doesn't contain new findings itself. The original research identified a microbe found living on plastic waste that can help remove pollution (nitrogen compounds) from wastewater even when microplastics are present, which could be useful for improving water treatment as plastic pollution continues to grow. Since this update only corrects a technical mistake, it doesn't change the study's overall conclusions.
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