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Correction to “Combined Exposure of Nano‐Titanium Dioxide and Polystyrene Nanoplastics Exacerbate Oxidative Stress‐Induced Liver Injury in Mice by Regulating the Keap‐1/Nrf2/ARE Pathway”
Summary
This notice is simply a correction to a previously published study, the authors fixed a mislabeled image but confirm all original findings and conclusions still stand. The underlying research found that combined exposure to nano-titanium dioxide (a common ingredient in sunscreens and food products) and nanoplastics caused more liver damage in mice than either substance alone, by triggering harmful oxidative stress. This matters because it suggests everyday exposure to multiple types of nanoparticles together, rather than just one at a time, could pose greater risks to liver health than previously understood.
T. Jia, P. Nie, and H. Xu, “Combined Exposure of Nano-Titanium Dioxide and Polystyrene Nanoplastics Exacerbate Oxidative Stress-Induced Liver Injury in Mice by Regulating the Keap-1/Nrf2/ARE Pathway,” Environmental Toxicology 39, no. 5 (2024): 2681–2691, https://doi.org/10.1002/tox.24141. In Figure 4G, due to an oversight during the final stages of image arrangement and typesetting, there was a misuse of the image that occurred in the NAC+NaP+TiO2 NP group (400×). The figure has now been corrected below, and the authors have provided the original images. The authors confirm that all the experimental results and corresponding conclusions mentioned in the article remain unaffected. FIGURE 4. The biochemical indicators after intraperitoneal injection of N-Acetyl-L-cysteine (NAC). (A–C) The body weight, liver weight, and liver coefficient of mice after 28-day gavage. (D) AKP, (E) ALT, and (F) AST enzyme activities in the liver. (G) Representative histological images of the liver following 28-day gavage, red circle represents infiltration of inflammatory cell, black circle represents cellular vacuoles and the yellow asterisk represents apoptosis (×200 and ×400; hematoxylin and eosin). Data represented as means ± SD. *p < 0.05, **p < 0.01. We apologize for this error.