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In vivo methylmercury toxicity is exacerbated by polystyrene microplastic exposure, leading to colon barrier disruption, gut dysbiosis, and systemic oxidative imbalance
Summary
Researchers found that co-exposure to polystyrene microplastics and methylmercury worsens biological harm beyond what either contaminant causes alone, disrupting the colon barrier, destabilizing gut microbiota, and triggering systemic oxidative imbalance — underscoring the importance of studying pollutant mixtures rather than individual contaminants in isolation.
evidence that combined PS-MP and MeHg exposure exacerbates some biological outcomes noted with individual contaminant exposure, indicating the importance of considering co-contamination scenarios in risk assessment of emerging pollutants.