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Letter to the Editor Concerning “Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles”
Summary
This letter discusses the problem of excess variance in nanoparticle size distribution measurements, which degrades accuracy in applications from lipid nanoparticle quality control to nanoplastic hazard assessment. The correspondence highlights how measurement precision limitations affect our ability to characterize nanoscale plastic particles in environmental and biomedical contexts.
The vexing error of excess variance in measurements of nanoparticle size distributions degrades accuracy in applications ranging from quality control of nanoparticle products to hazard assessment of nanoplastic byproducts.The particular importance of lipid nanoparticles for vaccine and medicine delivery motivates