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Per-and polyfluoroalkyl substances (PFAS) as a health hazard: Current state of knowledge and strategies in environmental settings across Asia and future perspectives
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This review examined how microplastics act as vectors for PFAS—so-called forever chemicals—by adsorbing and transporting these compounds through aquatic and terrestrial environments to increase combined toxic burden. The co-exposure risk is particularly concerning for human health because both microplastics and PFAS are persistent, and their interaction may amplify systemic toxicity beyond what either pollutant causes alone.
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This review identifies critical knowledge gaps in understanding how microplastics and PFAS (forever chemicals) interact and cause harm in aquatic environments after more than seven decades of production. Addressing these gaps is urgent because both contaminants persist indefinitely, accumulate in living organisms, and are now detectable in virtually every aquatic environment on Earth.
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