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Microplastics in Indoor Air and Dust: Characterization, Risk Factors, and Health Risks

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This review synthesizes global data on microplastic concentrations in indoor air and dust across different building types and income regions, finding that lower-middle-income countries — especially in Southeast Asia and South America — have the highest indoor airborne microplastic levels. The results underscore that humans face continuous inhalation, ingestion, and dermal exposure to microplastics in everyday indoor environments, with documented links to oxidative stress, inflammation, and multi-organ toxicity.

Microplastics (MPs < 5 mm) have become a growing concern in indoor environments, where their concentrations often exceed those outdoors. Familiar indoor sources include textiles, furniture, paints, and cleaning products, while factors such as ventilation type, occupancy level, and cleaning practices influence their abundance. This review synthesizes current findings on the occurrence, characterization, and risk factors of airborne and dust-borne MPs indoors in various indoor settings, and also based on continent and country income from high to low-income countries. Overall, airborne MP concentrations tend to be higher in lower-middle-income countries, particularly in Southeast Asia and South America, and are generally higher than in high-income regions. Advances in sampling and analytical techniques (including microscopy, FTIR, Raman spectroscopy, and pyrolysis-GC–MS) are discussed alongside the particles' physical and chemical properties. Evidence from toxicological studies demonstrates that inhalation, ingestion, and dermal exposure to MPs are linked to oxidative stress, inflammation, endocrine disruption, and organ-specific effects on the respiratory, digestive, reproductive, immune systems, and nervous systems. This review highlights the urgent need for harmonized monitoring protocols, comprehensive risk assessment, and effective mitigation strategies, such as improved cleaning, ventilation, and material substitution, to reduce exposure and safeguard human health in indoor environments.

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