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Common Chemical Plasticizer Di(2-Ethhylhexyl) Phthalate Exposure Exacerbates Coxsackievirus B3 Infection

Repositorio Institucional E-DocUR (Universidad Del Rosario) 2024 1 citation ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Ramina Kordbacheh, Madelyn Ashley, William D. Cutts, Taryn E. Keyzer, Shruti Chatterjee, Tyler J. Altman, Natalie G Alexander, Tim E. Sparer, Brandon J. Kim, Jon Sin

Summary

This study found that DEHP, a common plasticizer in PVC products, exacerbates Coxsackievirus B3 (CVB3) infection, suggesting plasticizer exposure may act as a proviral environmental factor. The findings highlight DEHP as a potential contributor to increased severity of viral infections and call for further investigation into its immune-disrupting mechanisms.

DEHP may represent a major environmental factor associated with the severity of CVB infection. Further understanding of how DEHP exacerbates infection may better elucidate its potential role as a proviral environmental factor.

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