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Sustainable Solutions for Eye Drop Plastic Waste: Challenges, Innovations, and Environmental Impact

Critical Reviews in Biotechnology 2025
Siddharth Gandhi, Michael Balas, Amandeep Rai

Summary

This review examines the substantial plastic waste burden generated by single-use ophthalmic eye drop bottles and evaluates sustainable alternatives including biodegradable materials, multidose preservative-free systems, and take-back recycling programs, emphasizing that patient safety and environmental sustainability can be achieved together through policy and design innovation.

Models

The widespread use of single-use plastic eye drop bottles in ophthalmology presents a significant environmental challenge. While essential for preventing contamination and ensuring patient safety, these bottles contribute to plastic waste due to their small size, multimaterial composition, and inadequate recycling infrastructure. This review examines the environmental impact of eye drop packaging across various ophthalmic conditions, including dry eye disease, cataract surgery, and glaucoma, highlighting the substantial cumulative burden of plastic waste and carbon emissions. The manuscript explores innovative solutions to mitigate this environmental footprint without compromising clinical standards. Key strategies discussed include product redesign using biodegradable materials, the adoption of multidose preservative-free systems, and the development of alternative drug delivery technologies like punctal plugs. Additionally, the importance of advanced recycling initiatives, such as specialized take-back programs, is emphasized. The paper also underscores the need for behavioral, institutional, and policy interventions, including educational campaigns, sustainable procurement practices, and the implementation of Extended Producer Responsibility (EPR) policies. By integrating these multifaceted approaches, the field of ophthalmology can align the critical priorities of patient safety and environmental sustainability, fostering a transition towards greener practices while maintaining high standards of care.

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