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Top-down generated micro- and nanoplastics reduce macrophage viability without eliciting a pro-inflammatory response
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This study investigated whether top-down mechanically generated micro- and nanoplastics from physically shredded plastic affect macrophage viability and inflammation. The particles reduced macrophage viability in a dose-dependent manner but did not elicit a classical pro-inflammatory cytokine response.
The online version contains supplementary material available at 10.1186/s43591-025-00138-5.
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