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Original research — experimental, observational, or case-control study. Direct primary evidence.
Human Health Effects
Nanoplastics
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Micro‐ and Nanoplastic Toxicity in Upper Respiratory Tract: A Scoping Review
The Laryngoscope2025
Score: 48
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Jérôme R. Lechien,
Mario Manto,
Jérôme R. Lechien,
Mejdeddine Al Barajraji,
Samira Benali,
Samira Benali,
Jérôme R. Lechien,
Samira Benali,
Antonino Maniaci,
Samira Benali,
Samira Benali,
Jean‐Marie Raquez
Samira Benali,
Jean‐Marie Raquez
Samira Benali,
Sophie Laurent,
Samira Benali,
Samira Benali,
Samira Benali,
Samira Benali,
Jean‐Marie Raquez
Jean‐Marie Raquez
Jean‐Marie Raquez
Jean‐Marie Raquez
Samira Benali,
Laurence Ris,
Jean‐Marie Raquez
Jean‐Marie Raquez
Jean‐Marie Raquez
Nicolas Massager,
Jean‐Marie Raquez
Jean‐Marie Raquez
Jean‐Marie Raquez
Jean‐Marie Raquez
Robin Baudouin,
Jean‐Marie Raquez
Stéphane Hans,
Stéphane Hans,
Philippe Dubois,
Philippe Dubois,
Mario Manto,
Jean‐Marie Raquez
Summary
This scoping review found that both exposed and unexposed humans have microplastics and nanoplastics detectable in nasal tissue and fluids, with mask wearing and old nasal lavage devices contributing to deposition, and experimental studies suggesting inflammatory tissue changes from upper respiratory tract NMP accumulation.
The current clinical and experimental studies demonstrate that both exposed and unexposed humans have nasal NMP detected in their nasal tissues and fluids. Mask wearing and the use of old plastic nasal lavage devices can contribute to this deposition. While experimental studies suggest changes in tissue and cell physiology, the toxicity of NMP in nasal tissue remains poorly investigated and has not been conclusively demonstrated.