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Efficacy of Three Vaccine Regimens Against Infectious Hematopoietic Necrosis Virus Transmission Potential in Rainbow Trout

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Juliette Doumayrou, Hannah Brown, Mary G. Frazier, Mary G. Frazier, Hannah Brown, Andrew R. Wargo Andrew R. Wargo Andrew R. Wargo Hannah Brown, Andrew R. Wargo

Summary

Researchers tested three vaccine regimens against infectious hematopoietic necrosis virus in rainbow trout and found that while the vaccines improved host survival, they provided minimal protection against virus transmission. The study suggests that current vaccines may have limited long-term effectiveness in field settings because vaccinated fish can still spread the virus to others. The findings highlight the need for vaccines that not only protect individual fish but also reduce disease transmission in aquaculture.

Body Systems

Hematopoietic

Models

Fish other

Collectively, our results suggest that existing IHNV vaccines that increase host survival provide minimal virus transmission protection in rainbow trout, which is likely to limit their long-term efficacy in the field. This work contributes to a growing body of evidence that enhancement of the transmission protection of IHNV and other vaccines will likely bolster disease reduction in the field.

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