Electrochemical and Surface‐Enhanced Raman Scattering Coupling for Dual‐Mode Sensing of Nanoplastics

The existence of nanoplastics (NPLs) in the environment has received continued attention in recent years due to their potential toxicological impacts. Nevertheless, there is a significant shortage of comprehensive considerations for the detection of NPLs. Specifically, the material, particle size, surface chemistry, and adsorption of xenobiotics of NPLs all shape their transport, toxicity, and environmental fate. Accurate NPL analysis is therefore essential for risk assessment and environmental monitoring. Surface‐enhanced Raman spectroscopy (SERS) and electrochemical (EC) sensing have made significant progress in the detection of plastic contaminants, especially NPLs, which rely on their high sensitivity, portability for real‐time applications in the field, and fascinating cost‐effectiveness. Unfortunately, the rational technological coupling of both of them (EC‐SERS) to improve NPLs detection performance has not yet been considered. In this perspective, the potential of EC‐SERS in the analysis of NPLs is elucidated, and the respective application strengths and advances of the two technologies are highlighted, as well as the opportunities and challenges of their coupling.