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The combined effects of microplastics and tetracycline on reactor performance and the fate of antibiotic resistance genes during the sludge anaerobic digestion
Summary
Isoliensinine, a plant-derived alkaloid, inhibits oral squamous cell carcinoma cell growth by activating the MAPK signaling pathway through microRNA-mediated mechanisms, triggering ROS accumulation, mitochondrial apoptosis, and cell cycle arrest. While not directly related to microplastic pollution, the study demonstrates microRNA pathways as targets relevant to understanding plastic-induced cellular toxicity mechanisms.
The combined impact of MPs and TC on ARG enrichment in sludge during mesophilic AD, where low-abundance bacteria may serve as potential hosts, warrants greater attention.