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SOP 09 Quality Assurance and Control (QA/QC) for Small Microplastic (<100 µm) Analysis in Biological/Human Samples

Environmental Science Processes & Impacts 2026
Beatrice Rosso, Elena Gregoris, Fabiana Corami, Marco Roman

Summary

An Italian research consortium published a detailed Standard Operating Procedure for QA/QC protocols governing the analysis of microplastics smaller than 100 µm in human biological samples, emphasizing contamination prevention and Micro-FTIR reproducibility. Standardized laboratory procedures are essential for generating reliable human biomonitoring data as microplastic detection in tissues and fluids becomes a growing field.

Standard Operating Procedure (SOP) defining the QA/QC protocols and laboratory practices required to minimize and monitor microplastic contamination during the processing of human biological samples, ensuring the integrity and reproducibility of subsequent Micro-FTIR spectroscopic analysis. This document was prepared by the team of the research project "Integrated systemic detection of pollutants in the human body" (INSYDE-HU), n. P2022RJCHC, CUP: H53D23010450001, funded by funded by the PRIN 2022 framework of the Italian National Recovery and Resilience Plan (PNRR). (2025-02-19)

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