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Intestinal serotonin signaling suppression: a novel mechanism for overfeeding exacerbation by nanoplastics and MC-LR in zebrafish
AI summary
This research investigated the use of plastic fibers as reinforcement in concrete mixtures, evaluating the mechanical properties and durability of plastic fiber-reinforced concrete compared to conventional formulations. The study explores plastic waste valorization through construction materials while assessing long-term microplastic release potential.
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Nanoplastics, Gut Microbiota, and Neurodegeneration
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Nanoplastics ingested via contaminated food and water can cross biological barriers and accumulate in gut tissue, where they disrupt the gut microbiota and may trigger neuroinflammatory pathways linked to neurodegenerative disease. This gut-brain axis disruption represents one of the most concerning potential mechanisms by which chronic nanoplastic exposure could harm human health.
Microplastics alter gut serotonin levels in the absence of overt intestinal inflammation 4808
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Researchers fed mice various sizes of polystyrene microplastics for 12 weeks and found that MPs altered gut serotonin levels and changed mucosal immune responses without causing overt intestinal inflammation, suggesting subtle disruption of gut signaling pathways.
The Toxicity of (Nano)Microplastics on C. elegans and Its Mechanisms
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Researchers reviewed the toxicological effects of micro- and nanoplastics on the model organism Caenorhabditis elegans, finding that these particles cause oxidative stress, reproductive impairment, developmental delays, and neurological dysfunction, with nanoplastics generally more toxic than microplastics due to their greater cellular penetration.
Novel Insights into Foodborne Microplastics-Enhanced Shoaling Behavior in Marine Korean Rockfish (Sebastes schlegelii) : Energy Deficiency-Driven Gut-Brain Axis Dysregulation
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Researchers fed Korean rockfish microplastics at environmentally relevant concentrations and traced a mechanistic chain from hepatic mitochondrial dysfunction and glucose disruption to systemic energy deficiency, showing that energy-deprived fish increased shoaling behavior as a compensatory strategy while microplastics simultaneously destabilized the gut-brain axis by disrupting neurotransmitter pathways and gut microbiota.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.