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The Biological Clock of Entropy: Quantifying "Time-to-Collapse" in Nanoplastic-Stressed Tissues

Zenodo (CERN European Organization for Nuclear Research) 2026
Peter Mikuláš, Peter Mikuláš

Summary

Scientists have developed a new way to predict how much time body tissues have before tiny plastic particles could potentially trigger cancer. The method measures how much damage these nanoplastics cause to cells versus how well the cells can repair themselves. This could help doctors identify health risks from plastic pollution before serious problems like cancer develop.

How much time does a biological system have before physical stress turns into malignancy? This paper introduces a predictive framework for determining the "Remaining Energetic Life" (REL) of tissue. We argue that cancer is the final stage of a time-dependent erosion of cellular hardware. By calculating the ratio between nanoplastic-induced ion leakage and mitochondrial repair capacity, we can estimate the temporal window before a thermodynamic phase transition (oncogenesis) occurs.

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