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Bibliometric Evaluation of the Relationship between Selenium and Breast Cancer: A Synopsis
Summary
A bibliometric analysis of the relationship between selenium and breast cancer mapped publication trends, key research themes, and international collaboration patterns in this field, identifying selenium's protective potential as a growing area of cancer prevention research.
Aim: To discover the relationship between breast cancer and selenium via bibliometric analysis, identify their current status in literature, and investigate the international research activity based on breast cancer and selenium publications. Method: The Web of Science Core Collection (WoS) database was used to retrieve the data. The keywords (“breast cancer”) and (“selenium”) were utilized in “topic” selection mode for the search. Bibliometric analysis was employed to evaluate the papers, and correlation analysis was performed to identify the associations between the number of publications and citation counts. Results: A total of 731 outputs were produced between 1980 and 2025. The USA was reported as the most productive and most cited country. The most productive journal, publisher, and institution were reported as “Biological Trace Element Research”, “Elsevier”, and “Harvard University”, respectively. The most cited journal was “Cancer Research and Treatment”, the most active funding institution was “National Institutes of Health NIH,” and “breast cancer” was the most common keyword. Conclusion: The analysis highlights a growing interest in the potential role of selenium in breast cancer prevention, diagnosis, and treatment. The findings also reveal emerging themes and knowledge gaps that warrant further investigation, particularly regarding selenium’s biological mechanisms and clinical applications. Overall, this analysis serves as a guide for future research directions and promote evidence-based advancements in breast cancer management related to selenium.