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Methylation patterns and mathematical models reveal dynamics of stem cell turnover in the human colon

Proceedings of the National Academy of Sciences 2001 51 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 40 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Simon Weonsang Ro, Bruce Rannala

Summary

Researchers investigated the dynamics of stem cell turnover in the human colon using methylation patterns as biomarkers, finding that mathematical modeling of these epigenetic marks can reveal the rates at which colonic stem cells divide and are replaced over time.

Body Systems

Digestive

Micro-nano plastics originating from the prevalent usage of plastics have raised increasingly alarming concerns worldwide. However, there remains a fundamental knowledge gap in nanoplastics because of the lack of effective analytical ...Plastics are now omnipresent in our daily lives. The existence of microplastics (1 µm to 5 mm in length) and possibly even nanoplastics (<1 μm) has recently raised health concerns. In particular, nanoplastics are believed to be more toxic since their ...

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